Corticosteroid myopathy presents as weakness and wasting of the proximal limb and girdle muscles and is generally reversible following cessation of therapy.
Corticosteroids inhibit intestinal calcium absorption and increase urinary calcium excretion leading to bone resorption and bone loss. Bone loss of 3% over one year has been demonstrated with prednisolone 10 mg per day. Postmenopausal females are particularly at risk for loss of bone density. Sixteen percent of elderly patients treated with corticosteroids for 5 years may experience vertebral compression fractures. One author reported measurable bone loss over two years in women on concomitant therapy with prednisolone mg per day and tamoxifen. [ Ref ]
It is believed that the psychoactive and myoactive effects of these drugs play a role in the development of such dependence. Best Bulking Steroid: D-BAL (Dianabol) ★ ★ ★ ★ ★
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Common Side effects Associated With Long-Term Steroid Use Long-term steroid use, including corticosteroid and anabolic steroids , and their prescribed amount, contribute to a number of potential health risks.