In March 2011, China's Ministry of Agriculture said the government would launch a one-year crackdown on illegal additives in pig feed, after a subsidiary of Shuanghui Group , China's largest meat producer, was exposed for using clenbuterol-contaminated pork in its meat products. A total of 72 people in central Henan Province, where Shuanghui is based, were taken into police custody for allegedly producing, selling or using clenbuterol.  The situation has dramatically improved in China since September 2011, when a ban of clenbuterol was announced by China’s Ministry of Agriculture. 
Health records shall contain the date the lot was established (if using the unique lot method), the first date the animal(s) may be shipped for slaughter considering the requirement for at least a 180 day recorded history prior to slaughter, the unique identifier, as well as record entries that indicate the date the illness was noticed, the details of the illness, the number of animals affected and date the illness was resolved. Each record event entry shall be accompanied by the initials of the person making the entry and date/time of the entry.
Alfatradiol binds to the ERα and ERβ with 58% and 11% of the relative binding affinity of 17β-estradiol.  However, it has 100-fold lower estrogenic activity relative to estradiol,  which may in part be due to differences in the intrinsic activity of the two compounds. [ citation needed ] On the other hand, alfatradiol has been found to bind to and activate the brain -expressed ER-X with a greater potency than estradiol, indicating that it may be the predominant endogenous ligand for the receptor.